Ariana Jose
Gainesville
Summary
Recent University of Miami PhD graduate with 10 years of research experience in molecular and neurobiology. Out-of-the-box thinker who enjoys new challenges. Skilled at planning and executing research projects, acquiring new techniques, and troubleshooting experimental and analytical roadblocks. Known for fostering a collaborative training environment in the lab by providing helpful guidance to fellow students.
Overview
9
9
years of professional experience
Work History
Predoctoral Research Associate
University of Miami
Miami
07.2019 - 08.2025
- Employed sophisticated in vivo calcium imaging and transgenic expression technology in combination with behavior experiments to test key hypotheses about how G-proteins and ion channels work together to modulate neural circuit activity in the model nematode worm Caenorhabditis elegans.
- Communicated my research findings effectively by collaborating with the principal investigator and a former student to write and publish two research manuscripts as the first author, presenting my work at departmental seminars and professional conferences, and writing several proposals for extramural funding.
- Fostered a collaborative training environment in the laboratory by supervising an undergraduate student's honors thesis research, giving advice and feedback to fellow trainees during weekly group meetings, and assisting them with their experimental design, protocols, and technical issues whenever needed.
- Took on essential laboratory management duties as needed by updating and oganizing group databases, monitoring inventory and ordering supplies, cleaning and autoclaving glassware, preparing essential reagents, cleaning shared equipmentdisposing of hazardous waste according to universit protocol, and communicating with suppliers and research support staff as needed to resolve issues.
Student Research Associate (Federal Work Study)
University of Florida
Gainesville
08.2016 - 08.2018
- Collaborated with a postdoctoral associate to conduct and publish a research project that identified amino acids on the viral capsid surface of adeno-associated virus serotype 5 (AAV5) key to its antigenic and gene transduction properties.
- Won a travel award for the 2018 annual meeting of the American Society of Gene & Cell Therapy, where I presented the findings of the AAV5 project.
- Conducted experiments in collaboration with faculty, postdocs and students on various projects on the structure and function of adeno-associated viruses.
Education
Ph.D. - Cellular Physiology & Molecular Biophysics
University of Miami
Miami, FL08.2025
Bachelor of Science - Biochemistry (Major), Bioinformatics (Minor)
University of Florida
Gainesville, Florida, FL08.2018
Skills
- Molecular Biology
- Cell Culture & Animal Husbandry
- Fluorescence & Confocal Microscopy
- Statistics & Data Visualization
- Python Programming
- Research Communication
- Student Training & Supervision
- Laboratory Management
Accomplishments
2018 Meritorious Abstract Travel Award, American Society of Gene & Cell Therapy
Publications
7. Jose A*, Dhakal P*, Signorelli R, Case C, Chaudhry S, Collins K. (2025) Rho signaling promotes cell excitability and synaptic transmission. (Accepted to Genetics with minor revisions in progress. Manuscript available on BioRxiv. *: co-first authors).
6. Jose A, Collins K. (2024) NALCN channels are not major targets of Gαo or Gαq modulation in the C. elegans egg-laying behavior circuit. MicroPubl Biol. doi: 10.17912/micropub.biology.001065. eCollection 2024. PMID: 38287929; PMCID: PMC10823792.
5. Mietzsch M, Eddington C, Jose A, Hsi J, Chipman P, Henley T, Choudhry M, McKenna R, Agbandje- McKenna M. (2021) Improved genome packaging efficiency of adeno-associated virus vectors using Rep hybrids. J Virol. 95(19):e0077321. doi: 10.1128/JVI.00773-21. PMID: 34287038; PMCID: PMC8428402.
4. Mietzsch M, Jose A, Chipman P, Bhattacharya N, Daneshparvar N, McKenna R, Agbandje-McKenna M. (2021) Completion of the AAV structural atlas: Serotype capsid structures reveals clade-specific features. Viruses. 13(1):101. doi: 10.3390/v13010101. PMID: 33450892; PMCID: PMC7828300.
3. Mietzsch M, Smith JK, Yu JC, Banala V, Emmanuel SN, Jose A, Chipman P, Bhattacharya N, McKenna R, Agbandje-McKenna M. (2020) Characterization of AAV-specific affinity ligands: Consequences for vector purification and development strategies. Mol Ther Methods Clin Dev. 19:362-373. doi: 10.1016/j.omtm.2020.10.001. PMID: 33145372; PMCID: PMC7591348.
2. Jose A, Mietzsch M, Smith JK, Kurian J, Chipman P, McKenna R, Chiorini J, Agbandje-McKenna M. (2018) High-resolution structural characterization of a new adeno-associated virus serotype 5 antibody epitope toward engineering antibody-resistant recombinant gene delivery vectors. J Virol. 93(1): e01394-18. doi: 10.1128/JVI.01394-18. PMID: 30333169; PMCID: PMC6288331.
1. Bennett A, Patel S, Mietzsch M, Jose A, Lins-Austin B, Yu JC, Bothner B, McKenna R, Agbandje-
McKenna M. (2017) Thermal stability as a determinant of AAV serotype identity. Mol Ther Methods Clin Dev. 6:171-182. doi: 10.1016/j.omtm.2017.07.003. PMID: 28828392; PMCID: PMC5552060.
References
References available upon request.
Timeline
Predoctoral Research Associate
University of Miami
07.2019 - 08.2025
Student Research Associate (Federal Work Study)
University of Florida
08.2016 - 08.2018
Ph.D. - Cellular Physiology & Molecular Biophysics
University of Miami
Bachelor of Science - Biochemistry (Major), Bioinformatics (Minor)
University of Florida