Summary
Overview
Work History
Education
Skills
Personal Information
Publications
Additional Information
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Aya Abouissa

Mannheim

Summary

Hardworking PhD Student committed to learning, developing skills in Cardiovascular Research and team contribution. Self-directed and energetic with superior performance in both autonomous or collaborative environments working independently and collaborating with others on group projects.

Overview

8
8
years of professional experience

Work History

PhD Student

Medical Faculty of Mannheim, Heidelberg University
2019.11 - Current

I am currently a PhD student in the Cardiovascular Physiology Department and Heidelberg Biosciences International Graduate School (HBIGS). My project is focused on understanding the mechanisms underlying cardiovascular adaptation to neonatal and adult cardiac pressure overload.


My Key Responsibilities:

  • Research and Experimentation:

- Design, plan, and execute experiments related to cardiovascular physiology, including but not limited to studies on cardiac functions, vascular biology, and molecular mechanisms of cardiac regeneration and adaptation to pressure overload.
- Utilize various techniques such as molecular biology, multiomics, cardiac organoids, imaging, and in vivo models (neonatal and adult TAC) to investigate cardiovascular phenomena.
- Analyze and interpret experimental data by developing custom bioinformatics tools and pipelines.

  • Literature Review and Hypothesis Development:

- Conduct comprehensive literature reviews to stay updated on current research trends and identify gaps in the field.
- Develop research hypotheses and design experiments, contributing to the overall goals of the research group.

  • Collaboration and Teamwork:

- Collaborate with other members of the research team, including postdoctoral researchers, technicians, and fellow PhD students, to ensure the successful completion of research projects (co-authorship in 5 publications in peer-reviewed journals).
- Participate in lab meetings, seminars, and departmental activities, contributing to the intellectual environment of the department.

  • Data Management and Reporting:

- Manage and organize experimental data, ensuring accuracy and reproducibility.
- Prepare and present research findings at internal meetings, conferences (2 poster prizes obtained), and in peer-reviewed publications.

Master of Science (Translational Medical Research)

University of Heidelberg
2017.07 - 2019.09

Master of Science in Translational Medical Research (M. Sc. TMR).

Thesis title:

"Investigation of Fibroblast-Cardiomyocyte and Fibroblast-Endothelial Cells Cross-Talk during Adaptation of Neonatal Mice to Cardiac Pressure Overload: Method Optimization"

Hospital and Clinical Pharmacist

Al-Attarin Clinic, Ministry of Health
2017.11 - 2018.08

Developed effective relationships with physicians, nurses, and other healthcare professionals to ensure optimal communication and collaboration in patient care.

  • Verified safety and accuracy of physician orders.
  • Maintained strict compliance with relevant laws, regulations, policies, and procedures related to hospital pharmacy practice.
  • Dispensed and procured medicinal products and supplies used in hospital.
  • Actively participated in hospital committees focused on enhancing patient safety through continuous performance improvement efforts.
  • Collaborated with interdisciplinary healthcare teams to optimize patient care plans, resulting in improved therapeutic outcomes.

Clinical Pharmacist in the ICU & CCU

Mabaret Al-Asafra Tertiary Hospital
2016.11 - 2017.11

Full-time Clinical Pharmacist in the Intensive Care Unit (ICU) and Critical Care Unit (CCU)

  • Evaluated medication regimens for complex patients, identifying potential drug interactions and devising alternative treatment strategies when necessary.
  • Help implementing an evidence-based approach to practice in the intensive & coronary care unit & ward.
  • Educated patients on proper medication use and adherence, leading to improved health outcomes and decreased hospital readmissions.
  • Advised physicians on how to properly dose medications.
  • Implemented cost-saving measures through formulary management and utilization review, ensuring efficient use of resources while maintaining high-quality patient care standards.
  • Contributed to antimicrobial stewardship efforts by monitoring antibiotic usage patterns and making recommendations for targeted improvements.
  • Collaborated with interdisciplinary healthcare teams for optimal patient care and improved treatment outcomes.

Teaching Assistant

Department of Pharmaceutics, Faculty of Pharmacy
2016.10 - 2017.05
  • Help & teach undergraduate students during the practical sessions in hospital pharmacy course.
  • Managed classroom behavior effectively, creating a positive learning atmosphere conducive to academic success.
  • Collaborated with fellow teaching assistants to create a consistent and supportive learning environment for students.
  • Helped with grading assignments and tests, providing constructive feedback to students based on results.
  • Facilitated activities in small groups to reinforce concepts taught by class teacher.

Education

Master of Science - Translational Medical Research

University of Heidelberg
Heidelberg, Germany
09.2019

Bachelor of Science - Clinical Pharmacy

Faculty of Pharmacy, Alexandria University
Alexandria, Egypt
07.2016

High School Diploma -

École Des Religieuses Fransiscaines Ibrahimie
Alexandria, Egypt
07.2011

High School Diploma -

Deutsch-Französisches Gymnasium
Saarbrücken, Germany
07.2009

Skills

General Skills

  • Fast Learner
  • Attention to Detail
  • Positive Attitude
  • Time Management
  • Team Collaboration

Multilingual:

  • English, German, Arabic and French

Lab Skills:

  • Bioinformatics Analyses Skills (Programming with R-Language and Python)
  • In-Vivo Animals Studies (Echocardiography, Doppler, Blood Pressure Measurement, Glucose Tolerance Testing, Surgeries: neonatal and adult Transverse Aortic Constriction)
  • In-Vitro Studies (Cell Isolations and Culture, 3D Cardiac Organoids, Functional Analyses, Molecular Biology Techniques)

Personal Information

Date of Birth:   01.10.1993

Place of Birth: Alexandria, Egypt

Current Citizenship: Egyptian

Publications

Trogisch FA, Abouissa A, Keles M, et al. Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Science Translational Medicine. 2024;16(736):eabq4581. (Co-author)


Froese N, Cordero J, Abouissa A*, et al. Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication. iScience. 2022;25(3):103965. (Shared first author)


Szaroszyk M, Kattih B, Martin-Garrido A, Trogisch F, Dittrich G, Grund A, Abouissa A, et al. Skeletal muscle derived Musclin protects the heart during pathological overload. Nature Communications. 2022;13. (Co-author)


Malek Mohammadi M, Abouissa A, Heineke J. A surgical mouse model of neonatal pressure overload by transverse aortic constriction. Nature Protocols. 2021;16(2):775-790. (Co-author)


Malek Mohammadi M, Abouissa A, Azizah I, et al. Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload–associated maladaptation. JCI Insight. 2019;4(16). (Co-author)

Additional Information

Prizes and Awards:

  • Cardiomyopathy Poster award 2nd prize, Retreat of the DZHK partner site Heidelberg/Mannheim, Germany, 2023.
  • 2nd poster prize, CRC1366 Vascular Control of Organ Function, Speyer, Germany, 2023

Signature

Place and Date

Timeline

PhD Student

Medical Faculty of Mannheim, Heidelberg University
2019.11 - Current

Hospital and Clinical Pharmacist

Al-Attarin Clinic, Ministry of Health
2017.11 - 2018.08

Master of Science (Translational Medical Research)

University of Heidelberg
2017.07 - 2019.09

Clinical Pharmacist in the ICU & CCU

Mabaret Al-Asafra Tertiary Hospital
2016.11 - 2017.11

Teaching Assistant

Department of Pharmaceutics, Faculty of Pharmacy
2016.10 - 2017.05

Master of Science - Translational Medical Research

University of Heidelberg

Bachelor of Science - Clinical Pharmacy

Faculty of Pharmacy, Alexandria University

High School Diploma -

École Des Religieuses Fransiscaines Ibrahimie

High School Diploma -

Deutsch-Französisches Gymnasium
Aya Abouissa