Hardworking PhD Student committed to learning, developing skills in Cardiovascular Research and team contribution. Self-directed and energetic with superior performance in both autonomous or collaborative environments working independently and collaborating with others on group projects.
I am currently a PhD student in the Cardiovascular Physiology Department and Heidelberg Biosciences International Graduate School (HBIGS). My project is focused on understanding the mechanisms underlying cardiovascular adaptation to neonatal and adult cardiac pressure overload.
My Key Responsibilities:
- Design, plan, and execute experiments related to cardiovascular physiology, including but not limited to studies on cardiac functions, vascular biology, and molecular mechanisms of cardiac regeneration and adaptation to pressure overload.
- Utilize various techniques such as molecular biology, multiomics, cardiac organoids, imaging, and in vivo models (neonatal and adult TAC) to investigate cardiovascular phenomena.
- Analyze and interpret experimental data by developing custom bioinformatics tools and pipelines.
- Conduct comprehensive literature reviews to stay updated on current research trends and identify gaps in the field.
- Develop research hypotheses and design experiments, contributing to the overall goals of the research group.
- Collaborate with other members of the research team, including postdoctoral researchers, technicians, and fellow PhD students, to ensure the successful completion of research projects (co-authorship in 5 publications in peer-reviewed journals).
- Participate in lab meetings, seminars, and departmental activities, contributing to the intellectual environment of the department.
- Manage and organize experimental data, ensuring accuracy and reproducibility.
- Prepare and present research findings at internal meetings, conferences (2 poster prizes obtained), and in peer-reviewed publications.
Master of Science in Translational Medical Research (M. Sc. TMR).
Thesis title:
"Investigation of Fibroblast-Cardiomyocyte and Fibroblast-Endothelial Cells Cross-Talk during Adaptation of Neonatal Mice to Cardiac Pressure Overload: Method Optimization"
Developed effective relationships with physicians, nurses, and other healthcare professionals to ensure optimal communication and collaboration in patient care.
Full-time Clinical Pharmacist in the Intensive Care Unit (ICU) and Critical Care Unit (CCU)
General Skills
Multilingual:
Lab Skills:
Date of Birth: 01.10.1993
Place of Birth: Alexandria, Egypt
Current Citizenship: Egyptian
Trogisch FA, Abouissa A, Keles M, et al. Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Science Translational Medicine. 2024;16(736):eabq4581. (Co-author)
Froese N, Cordero J, Abouissa A*, et al. Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication. iScience. 2022;25(3):103965. (Shared first author)
Malek Mohammadi M, Abouissa A, Heineke J. A surgical mouse model of neonatal pressure overload by transverse aortic constriction. Nature Protocols. 2021;16(2):775-790. (Co-author)
Malek Mohammadi M, Abouissa A, Azizah I, et al. Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload–associated maladaptation. JCI Insight. 2019;4(16). (Co-author)
Prizes and Awards:
Place and Date