Ivan Dalyuk

In this role, I studied changes in the nuclear organization of human fibroblasts during adhesion. I utilized immunostaining and spinning disk confocal microscopy to monitor dynamics of chromatin and its post-translational modifications. Furthermore, I examined morphological alterations in the nucleus and nuclear envelope. Additionally, I analyzed the correlation between the nuclear shape and the ratio of nuclear lamins. To conduct this analysis, I developed a series of automated scripts using the ImageJ-Macro, MATLAB, and Python programming languages.

During this internship I used Atomic Force Microscopy (AFM) and Traction Force Microscopy (TFM) to investigate the mechanics of HeLa cells during cell division

The goal of this internship was to study biomolecular recognition between aptamers and small molecules using Bio-Layer Interferometry and Quartz Crystal Microbalance with Dissipation techniques.