Summary
Overview
Work History
Education
Skills
Software
Publications
Certification
Timeline
Generic
Lukas Krauß

Lukas Krauß

Computational Biologist
Eisenacher Straße 13 37085 Göttingen,

Summary

Meticulous and analytical researcher in the field of cancer biology and epi-genetics. Adaptive team player with in-depth knowledge of data analysis, gene regulation and protein degradation with a keen interest in improving and learning new skills in the field of computational biology.

Overview

6
6
years of professional experience
21
21
years of post-secondary education
2
2
Certifications
2
2
Languages

Work History

Research Associate

Universitätsmedizion Göttingen (UMG)
09.2021 - Current
  • Setup of novel laboratory infrastructure
  • Integration of HPC-cluster workflow for OMICs data analysis
  • Compiling and curation of publicly available datasets
  • Analysis and interpretation of sequencing data as well as design and execution of wet-lab validation experiments
  • Supervision of medical and master students
  • Presentation of research results at scientific conferences

Research Associate

Klinikum rechts der Isar (TUM)
07.2018 - 08.2021
  • Establishment and maintenance of lab internal RNA-seq workflow and management of public OMICs data storage
  • Project supervision and task delegation of medical doctorate students
  • Cooperation with academic groups for development and testing of novel chemical compounds

Education

Dr. Rer. Nat. - Experimental Medicine

Technical University Munich
Munich, Germany
07.2018 - Current

Master of Science - Molecular Biotechnology

Technical University Munich
Munich, Germany
04.2015 - 04.2018

Bachelor of Science - Molecular Biotechnology

Technical University Munich
Munich, Germany
10.2010 - 03.2015

Allgemeine Hochschulreife -

Liselotte-Gymnasium
Mannheim, Germany
09.2002 - 06.2010

Skills

    OMICs Data Analysis

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Software

R/R-Studio

Unix/Linux

Python

MSOffice

Publications

  • Krauss, L.*, Schneider, C., Hessmann, E., Saur, D., Schneider, G.* Epigenetic control of pancreatic cancer metastasis. Cancer Metastasis Rev 42, 1113–1131 (2023).


  • Krauss L.*, Urban B.*, Hastreiter S.*, Schneider C.*, et al. "Hdac2 Facilitates Pancreatic Cancer Metastasis." Cancer Res 82.4 (2022): 695-707.


  • Abdelsalam M.*, Ibrahim H. S.*, Krauss L*.,et al. "Development of Pyrazine-Anilinobenzamides as Histone Deacetylase Hdac1-3 Selective Inhibitors and Biological Testing against Pancreas Cancer Cell Lines." Methods Mol Biol 2589 (2023): 145-55.


  • Orben F., Lankes K., et al. "Epigenetic Drug Screening Defines a Prmt5 Inhibitor-Sensitive Pancreatic Cancer Subtype." JCI Insight 7.10 (2022).


  • Schneeweis C., Diersch S., Hassan Z., et al. "Ap1/Fra1 Confers Resistance to Mapk Cascade Inhibition in Pancreatic Cancer." Cell Mol Life Sci 80.1 (2022): 12.


  • Lier S., et al. "A Novel Cereblon E3 Ligase Modulator with Antitumor Activity in Gastrointestinal Cancer." Bioorg Chem 119 (2022): 105505.


  • Schneeweis C., et al. "Indirect Targeting of Myc Sensitizes Pancreatic Cancer Cells to Mechanistic Target of Rapamycin (Mtor) Inhibition." Cancer Commun (Lond) 42.4 (2022): 360-64

Certification

Statistics and R - edX/HarvardX

Timeline

Statistics and R - edX/HarvardX

03-2024

Using the GWDG Scientific Compute Cluster-An Introduction - GWDG

11-2021

Research Associate

Universitätsmedizion Göttingen (UMG)
09.2021 - Current

Research Associate

Klinikum rechts der Isar (TUM)
07.2018 - 08.2021

Dr. Rer. Nat. - Experimental Medicine

Technical University Munich
07.2018 - Current

Master of Science - Molecular Biotechnology

Technical University Munich
04.2015 - 04.2018

Bachelor of Science - Molecular Biotechnology

Technical University Munich
10.2010 - 03.2015

Allgemeine Hochschulreife -

Liselotte-Gymnasium
09.2002 - 06.2010
Lukas KraußComputational Biologist