Mariangela Spagnuolo

Creative problem-solver with a passion for using research to uncover valuable insights. Adept at utilizing new technologies and tools to address complex challenges. Demonstrated ability to build consensus and drive collaboration across diverse teams.

• 2020-2022, Practicum teacher, Cellular and Molecular Biology, JGU
• 03/19-08/19, Master student supervisor, IMB, Mainz
• 07/17-08/17, Visiting student supervisor, IMB, Mainz

• Sklias A, Cruciani S, Marchand V, Spagnuolo M, Lavergne G, Bourguignon V, Brambilla A, Dreos R, Marygold SJ, Novoa EM, Motorin Y, Roignant JY (2024) Comprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster, NAR, gkae139
• Leismann J*, Spagnuolo M*, Pradhan M, Wacheul L, Vu MA, Musheev M, Mier P, Andrade-Navarro MA, Graille M, Niehrs C, Lafontaine DL, Roignant JY (2020) The 18S ribosomal RNA m6A methyltransferase Mettl5 is required for normal walking behavior in Drosophila melanogaster, EMBO Rep., 21, 7, e49443
• Fellows R, Denizot J, Stellato C, Cuomo A, Jain P, Stoyanova E, Balázsi S, Hajnády Z, Liebert A, Kazakevych J, Blackburn H, Corrêa RO, Fachi JL, Sato FT, Ribeiro WR, Ferreira CM, Perée H, Spagnuolo M, Mattiuz R, Matolcsi C, Guedes J, Clark J, Veldhoen M, Bonaldi T, Vinolo MAR, Varga-Weisz P. (2018) Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases, Nat Commun, 9, 105

• Developmental Biology, Brain development
• Molecular Biology, Epitranscriptomics, Gene regulation, RNA metabolism, Translation, Ribosome heterogeneity

• 2022 EMBO short travel fellowship (Prof. Dr. David Gatfield’s lab, Lausanne, Switzerland)
• 2019 Poster award (STORM Therapeutics Conference, St Catharine’s college, Cambridge, UK)
• 2016 Erasmus scholarship (Prof. Varga-Weisz, Babraham institute, Cambridge, UK)
• 2015 Erasmus scholarship (Dr. Casanueva, Babraham Institute, Cambridge, UK)
• 2014 Top 3 students from University of Siena (King’s college, Cambridge, UK)
• 2013 Erasmus scholarship (University of Leicester, Leicester, UK)

Prof. Dr. Jean-Yves Roignant         Dr. Laetitia Chauve              Prof. Dr. Rene Ketting

University of Lausanne                  Trinity College, Dublin         IMB Mainz

jean-yves.roignant@unil.ch             chauvel@tcd.ie                       R.Ketting@imb-mainz.de