Negar Nejati

With a robust four-year research background, I am currently serving as a Researcher at the Cell, Gene, and Tissue Research Center of Tehran University of Medical Sciences. Actively engaged in the Hematopoietic Stem Cell Transplantation (HSCT) process, I have developed a keen interest in Immunotherapy and Cell Therapy. Under the guidance of esteemed professors, I have conducted several systematic reviews, particularly focusing on CAR-T-cell therapy for cancer treatment within this domain.

During the final two years of my medical education, I delved into Tissue Engineering research as a Researcher at both the Histopathology Laboratory and Animal Research Laboratory. These roles have not only enriched my understanding but also honed my skills in various laboratory techniques.

• systematic review and meta-analysis research design Internship

I learned essential tasks such as formulating precise research questions, conducting thorough literature searches, selecting relevant studies based on predefined criteria, extracting data, critically appraising study quality, synthesizing data using statistical techniques when appropriate, and effectively interpreting and reporting findings. 

• Workshop for Working with laboratory animals

I acquired crucial skills in ethical and practical aspects of animal care for research purposes. This involved grasping principles of animal welfare and regulatory compliance, mastering safe handling and restraint techniques, and gaining proficiency in common experimental procedures.

• Tissue Engineering Internship

I acquired practical skills and theoretical knowledge essential for tissue engineering and regenerative medicine. This encompassed learning cell culture techniques, tissue characterization methods, bioreactor systems, applications in regenerative medicine, and ethical considerations.

• Primer Design Workshop

I learned primer design fundamentals, analyzing sequences to identify target regions, using primer design software, ensuring primer specificity and efficiency, validating primers experimentally, troubleshooting common issues, and applying primer design techniques in various molecular biology applications

• Stem Cell for Researchers Text Book (Chapter number 7) (published)
• A Systematic Review and Meta-analysis on the Safety and Efficacy of CAR T Cell Therapy Targeting GPRC5D in Patients with Multiple Myeloma; A New Insight in Cancer Immunotherapy (submitted)
• The Efficacy and Applicability of Chimeric Antigen Receptor (CAR) T cell-based Regimens for Primary Bone Tumors: A Comprehensive Review of Current Evidence (submitted)
• The Hematopoietic Stem Cell Transplantation Outcome in Chronic Granulomatosis Disease Pediatric Patients: BCG vaccinated vs. non-BCG vaccinated Patients (submitted)
• Evaluation of microfluidic encapsulation of estrogen in calcium alginate beads in vitro and in rat dermal would healing (submitted)
• Study of the estrogen treatment in gene expression and wound closure in co-cultured fibroblast and endothelial cells (submitted)
• CD7 Targeting T Cell Specific Therapy for Acute Lymphoblastic Leukemia; A Systematic Review and Meta-Analysis (submitted)
• The Complex Role of Macrophages in Pancreatic Cancer Progression and Potential Therapeutic Targets (submitted)
• A Survey on Cytomegalovirus Infection and its Medication on the Ramifications and Outcome post Hematopoietic Stem Cell Transplantation in Pediatric Patients (to be submitted)
• Investigating factors related to hemorrhagic cystitis and its prognosis after hematopoietic stem cell transplantation in children (to be submitted)

• Prof. Amir Ali Hamidieh, Professor of Pediatric Oncology, Pediatric Cell & Gene Therapy Research Center, +989121593270, aahamidieh@tums.ac.ir
• Prof. Atefeh Shamosi, Professor of Medicine Department, Alborz University of Medical Science, +989213655925, a.shamosi@abzums.ac.ir
• Prof. Maryam Behfar, Professor of Pediatric Oncology, Pediatric Cell & Gene Therapy Research Center, +989125570286, behfarm@sina.tums.ac.ir