NITISH SABHARWAL

WUP_CMCT: Ongoing [Apr '25 - Present]

Lead method validation team to establish new ELISA assay (in ADCQ) for PSMA-TAC Launch, serving as a Catalyst.

MYR_QU: Creating impact, Faster work cycles [Oct ’24 – Mar ‘25]

Retest Project; Defined 90-day team goal. Delivered more value, more quickly and more effectively. (Visionary, Architect)

Guided RM lab as a Coach to stay focused on critical KPIs during redesign of their L1-format. (Received in lab, Planning Adherence, On-time Delivery).

Benchtop Analysis: Critical for resource planning in QC RM lab. Engaged with multiple stakeholders on different levels to perform analysis.

GRZ_OE Dept.: Delivering Value and Continuous improvement [Feb – Sep ‘24]

MU Dashboard: Brought together cross-functional team to deliver greater value as a Catalyst.

Triggered workflow optimization -> automated generation of MU dashboard resulting in a huge efficiency gain. (Architect)

Co-Led envisioning and execution of IFLP Trainee/Alumni Meet 2024 and related activities on-site in GRZ. (Visionary, Architect)

‘Bulk-Fill’ Pilot: New bulk filling parameters delivering ~1000€/week savings on single line using a data-driven approach.

• Establishing micro-fluidics based approach as part of project aimed at improving oncology management using AI tools.
• Learning applications and ethical implications of AI in healthcare.
• Communicate project objectives to founders and potential collaborators.
• Learn about medical/wearable device design requirements.

• Quantifying inter-cellular protein in MSCs with Western blot assay.
• Handling of organoid systems, bone tissue sectioning and histology methods.
• Communicated with partner institutes to set-up an internal tissue sectioning and histology facility.
• Literature reviews to identify quality reagents for handling bone organoids in-vitro.

• Developed epigenetic modifier (CRISPRa) system which showed an 8-fold increase in gene expression at target region.
• Designed DNA plasmids in-silico and cloned them in-vitro using molecular techniques.
• Transfected HEK 293T cells using using non-viral delivery methods.
• Performing gene expression analysis in NUFF fibroblasts using RT - qPCR.
• Presenting progress reports and final achievements to program/institute directors and examiners. Thesis Grade: 1.7.

• Achieved 90% gene knockout in prostate cancer cells using CRISPR/Cas9.
• Designing primers and oligonucleotides using SnapGene and BLAST software.
• Electroporating RNPs in C4 - 2 cells using Lonza 4D device.
• Gathered, arranged, analysed research data to create a report summarising the current state of immunotherapies against tumours. Grade 1.0