Zahra Erfanian Ghassab

I graduated as a general practitioner from the Public University of Medical Sciences in Birjand at the end of 2017.Then I completed a one-year mandatory medical service as an emergency medicine physician at Atshadast Nehbandan Hospital. At the same time, I worked as an emergency physician at Milad Hospital in Birjand for one year. After that, in early 2019, I moved to Tehran, the capital of Iran, to advance my career and enhance my skills. Initially, I obtained a medical practice license for Salehiyeh, a suburb of Tehran, and established a clinic there. At the same time, I worked both at my clinic and at Imam Hossein Hospital in Baharestan. Later, I completed courses in aesthetic procedures and cosmetic surgeries. After that, I obtained a medical practice license in Tehran and began working in two aesthetic clinics in the city, where I have been practicing ever since.

LinkedIn: Samira Erfanian

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• Date of Birth: 03/11/91
• Marital Status: Married

• The maternal reduced uteroplacental perfusion of preeclampsia induces sexually dimorphic metabolic responses in rat offspring, Biology of Sex Differences, 2022
• The impact of long-term consumption of diets enriched with olive, cottonseed or sesame oils on kidney morphology: A stereological study, Annals of the Brazilian Academy of Sciences, 2019

Along with my professors, I co-authored two articles during my studies and after graduation, both of which were published in reputable journals.

The impact of long-term consumption of diets enriched with olive, cottonseed and sesame oils on kidney morphology: A stereological study. It published in annals of the Brazilian Academy of Sciences (2019).

methods: Together with my professors, we conducted this research project, the aim of this study was to evaluate the impact of long-term consumption of olive, cottonseed and sesame oils on renal morphology in rats. 70 male Wistar rats randomly assigned into seven equal groups and treated with standard diet (control), the standard diet enriched with 10% or 20% (W/W) of either olive oil (OLI10%, OLI20%), cottonseed oil (COT10%, COT20%) or sesame oil (SES10%, SES20%) for 5 months. Quantitative features of the kidney including kidney and cortex volumes and the number of glomeruli were analyzed stereologically.

Result: All of the studied oils in low concentration had no devastating effects on renal morphology and also its pathological features. However, only in SES20% group, kidney volume as well as, cortical volume was higher than the control group. Besides, accumulation of carbohydrate macromolecules and renal fibrosis were markedly increased in SES20% group compared to the control. The results suggest that sesame oil, especially at high concentration, may lead to renal deformities as a result of histopathological changes such as dilatation, fibrosis, and tubular defects.

The maternal reduced uteroplacental perfusion model of preeclampsia induces sexually dimorphic metabolic responses in rat offspring. It published in Biology of Sex Differences (2022).

Methods: Timed pregnant Wistar rats underwent RUPP or sham surgeries on day 14 of gestation. Glucometabolic parameters were evaluated on postnatal days (PND), 14 (childhood), and 60 (young adult). In addition, intraperitoneal glucose tolerance test (IPGTT), homeostatic model assessment of insulin resistance (HOMA‑IR), immunohistochemical staining for insulin in pancreatic islets, arterial blood pressure and 24‑h urine protein (24hUP) excretion were performed at PND60.

Results: Male, but not female, young adult rats (PND60) of RUPP dams exhibited an impaired IPGTT, decreased circulatory insulin and weakened pancreatic insulin immunoreactivity. Compared to the male offspring of the sham group, the body mass of male RUPP offspring significantly caught up after PND42, but it was not sex‑specific. RUPP pups also exhibited upregulations in glucagon (only males) and ghrelin (both sexes with a more significant increase in males) during PND14–PND60. However, in sham offspring (both sexes), glucagon levels were downregulated and ghrelin levels unchanged during PND14–PND60. The blood pressure, HOMA‑IR and 24hUP values did not alter in RUPP pups.