Wolfgang Kessler

Head of Fermentation
- Fermentation of recombinant bacteria and primary separation (centrifugation, cell-desintegration, filtration)
- Production of enzymes and cell lysates

• Internal consultant for technological issues in bioprocess and dermal filler production.
• Market recherche
• Assesment of technoloy

• Customer in US Pharma business
• Communication with customer
• Communication with internal team in different sites covering the complete value chain
• Contactual negotiations

• expansion of facility for the production of dermal filler,
• responsible for process equipment and utilities (pharma water Systems, clean gases)
• Maintenance
• optimization of process equipment
• Set up of new QC laboratory 8planning layout, negotiation with vendors, commissioning, order, installation)

• Setup of new facility for the production of dermal filler
• responsible for process equipment and utilities (pharma water Systems, clean gases)
• Engineering Support for Technology Transfer
• Development /optimization/addaptation of production Equipment
• Close cooperation with R&D department
• Supervision of batchelor and master students (thesis)

• Setup of new production facility for microbial fermentation (biological safety Level 2) and protein recovery and purification.
• FDA compliance of API production plants at site Dessau
• Responsible for process equipment and utilities.

• Setup of new clean room facility for the biotechnological production of protein, biological safety level 2
• responsible for process equipment and utilities (pharma water Systems, clean gases)
• Qualification (DQ to OQ)
• Commissioning
• Communication with external engineering partner
• Communication with internal customers

• fermentation of gliding bacteria (myxobacteria and others, slow growing), fungi, E. coli, yeast (e.g. Picca)
• fermentation up to 2000 L scale
• DSP (centrifugation, filtration, extraction, freeze drying)

• Qualtiy assurance for GMP facility
• internal audits (planning, execution, follow up)
• external audit (customer, authorities)
• training of staff (general GMP, clean-room, etc.)
• writing SOP's
• document control
• CAPA

• fermentation (E. coli, yeast (Picchia, Hansenula, etc.), gliding bacteria
• fermentation up to 5000 L scale
• process documentation
• measurement and control technology

• Performing and evaluation of GC-MS, GC and HPLC analytics
• Maintenance of analytical equipment
• Commissioning of new analytical equipment
• Set up of new laboratory in cooperation with facility management